ES Chakravarthy’s insights show that engineers with an entrepreneurial mindset can build sustainable value in their domains. In the following paper, we reveal how innovation, risk-taking, market sensitivity, leadership, vision, and business strategy enable the engineer to advance from technique and make a difference. For an engineer as a founder of a start-up or an engineer within the organization, the principles of entrepreneurship help him or her to take initiative in the creation of a new reality and redefine success in the new millennium.